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Zhao and colleagues developed an innovative two-stage nanoengineering strategy, using a gadoliniumeuropium metalorganic framework (GdEuMOF) loaded with tirapazamine (TPZ), designed to amplify TPZ activation through exacerbated hypoxia in breast tumors during microwave hyperthermia
A gradual dose-escalation is recommended for liraglutide 3.0 mg, starting with the initial dose of 0.6 mg per day for 1 week, then increasing the dose in weekly increments until the maximum therapeutic dose of 3.0 mg is reached [21]
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Mini reviews in medicinal chemistry
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