Dosage should begin conservatively and adjust based on tolerance and clinical markers
Meet the experts Azadeh Shirazi, MD, a board-certified dermatologist in La Jolla, CA Heather Woolery-Lloyd, MD, a board-certified dermatologist in Miami, Florida Jeanette Graf, MD a board-certified dermatologist in New York, New York Nicole Lee, MD, board-certified dermatologist in Garden City, New York Reshmi Kapoor, MD, a board-certified dermatologist in New York City How we test and review products When Allure tests a product, our editors look at it from every angle to best serve you
Summer can increase irritation risk because people layer sunscreen, cosmetics, after-sun gels, fragrances, and active skincare while the skin is exposed to heat, sweat, and ultraviolet radiation
The peptide appears to influence angiogenesis, the formation of new blood vessels, which is crucial for tissue repair processes
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A 2025 systematic review found modest skin-lightening effects in several oral trials, but also variable study quality and effects that were not sustained after stopping