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The 2025 IV pilot measured cardiac, hepatic, renal, thyroid, and glucose biomarkers and reported no abnormalities (Lee et al., 2025), which gives a sense of what those investigators considered worth checking

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Keep a written log of your reconstitution date, water volume used, and resulting concentration

Neurological and Neurodegenerative Conditions Neurological applications remain highly preliminary based on animal model studies

Populations of particular concern based on mechanism and the absence of human data include: individuals with active or suspected malignancy (pro-angiogenic preclinical profile)