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3.2 Dosing instructions / Titration Often taken twice daily, with doses gradually increasing until reaching 32 mg naltrexone / 360 mg bupropion by week 4
Impact of hormonal imbalance on mood, energy, and cycle regularity Hormonal symphony Plummeting estrogen diminishes serotonin and GABA action, inducing mood swings, poor stress defense and sleep difficulties
Hirafuji M et al
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