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Other observational studies have linked GLP-1 drugs to lower rates of new and recurring alcohol use disorder, reduced diagnoses and relapse in cannabis use disorder, fewer health care visits for nicotine dependence and lower risk of opioid overdose
Our choice of an active-comparator design was intended to reduce confounding by indication, severity of diabetes mellitus and unmeasured clinical characteristics, as basal insulin is used in similar clinical settings and stages of type 2 diabetes as GLP-1RAs [16]
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Future developments may include: Broader Clinical Trials Researchers are investigating how GLP-1 medications may benefit individuals without diabetes but with high cardiovascular risk, potentially leading to expanded FDA approvals for heart disease prevention
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Research shows that protein-rich meals improve GLP-1 response and appetite control
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