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Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood

Most patients dont require any topical anesthesia, though it can be used if requested

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Without sufficient B12, one's energy levels can plummet , leading to fatigue and lethargy