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Description

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10.1007/s00429-014-0714-z Summary Keywords GLP-1, obesity, diabetes, CNS, insulin Citation Heppner KM and Perez-Tilve D (2015) GLP-1 based therapeutics: simultaneously combating T2DM and obesity

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The trial lasted 48 weeks with a standardized lifestyle intervention including diet counseling and physical activity recommendations

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Another study with CuCl 2 treated Hep G2 cell line demonstrated that mitochondrial toxicity is an intermediate-level event associated with copper toxicity to Hep G2 cells while lysosomal damage is the early event and plasma damage a late feature associated with copper toxicity 34

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