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Also, when challenged with APAP, mice exposed to HFD showed a significantly downregulation of cytoprotective enzymes coding genes glucose 6-phosphate dehydrogenase (G6pdh) and NAD(P)H dehydrogenase 1 (Nqo1) as compared to their CD counterparts (Fig

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J Hepatol 56:10701079 Antoine DJ, Dear JW, Lewis PS, Platt V, Coyle J, Masson M, Thanacoody RH, Gray AJ, Webb DJ, Moggs JG, Bateman DN, Goldring CE, Park BK (2013) Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital