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The liver and kidneys have the highest concentrations of glutathione, followed by the lungs and small intestine, which is closely related to the detoxification functions of these organs

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For example, a small number of subjects reported the following mild side effects in the course of a four-week glutathione study at the dose of 1g/day [13]: Flatulence Loose stools Flushing Weight gain In a more specialized study involving cystic fibrosis patients and much higher glutathione doses, some of the patients reported tightness in the torso, diarrhea, and fever-like symptoms [14]