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NICE guidance recommends initial treatment with hydroxocobalamin 1mg intramuscularly three times weekly for two weeks, followed by maintenance therapy
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Read on to discover if your symptoms fit those of B12 deficiency so you can determine if you might be a candidate for these injections
Multi- and single-channel pipettes and sterile pipette tips
Studies have explored how the compound engages the beta common receptor subunit in contexts such as peripheral nerve function and pancreatic beta-cell survival
GPs can prescribe B12 injections following appropriate investigation, which should include: Full blood count to identify macrocytic anaemia Serum B12 and folate levels to confirm deficiency (using laboratory-specific reference ranges) Methylmalonic acid and/or homocysteine when B12 results are borderline Intrinsic factor antibodies if pernicious anaemia is suspected Additional tests depending on clinical presentation (e.g., thyroid function, coeliac serology) When both B12 and folate deficiency are present, B12 should be replaced before folate to avoid precipitating subacute combined degeneration of the spinal cord
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