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[31] [32] However, in 2003-2012, the National Institutes of Health (NIH) sponsored a $30 million controlled trial of chelation therapy, conducted by their National Center for Complementary and Alternative Medicine (NCCAM)

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3.2 Ceramides affect the electron transport chain (ETC) and promote ROS generation Mitochondria integrates the ETC to the oxidative phosphorylation to regulate cellular energy metabolism

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The concentration of GSH is at high levels, and GSSG and ROS are at depressed levels to maintain redox homeostasis in cardiomyocytes

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