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In such cases, someone with the MTHFR gene variation may seem to have elevated levels of B12 (as well as elevated levels of homocysteine), but will actually have low levels of B12 in the form that their body can utilize

For skin and connective tissue support, some researchers layer in GHK-Cu for wound healing

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Important caveat: the combination is not clinically validated

Given these potential side effects, RELATED QUESTIONS

Conclusion: Optimizing Your Vitamin B12 Therapy Getting the most out of vitamin B12 therapy is key to good health