A serum B12 level above 300 picograms per milliliter (pg/mL) is considered normal
But the solution only lasts 4 to 8 weeks
When B12 runs low, symptoms tend to creep in slowly enough to get blamed on something else: persistent fatigue, brain fog, low mood, weight gain or difficulty losing weight, weakness, tingling in the hands or feet, shortness of breath, and a weakened immune system
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Since this 2012 publication, there has been very little new research into this question
Freezing can also happen if you put the Wegovy pens directly on ice or ice packs as direct exposure to ice can freeze the medication