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For example, zileuton (226), red-kerneled rice proanthocyanidin (227), malabaricone C (228), caffeic acid (89), lysionotin (229) and magnolin (230) inhibit AA lipoxygenase by inhibiting the expression of key enzymes or enzyme activity reduction to achieve the anti-inflammatory effects (231236), the specific drugs used are shown in Table 6
Modules correlated with the KO genotype were enriched for neuronal and synaptic genes involved in vesicle-mediated transport, neurotransmitter secretion, and GTPase activity, suggesting that RAMP deletion disrupts synaptic signaling networks critical for metabolic regulation [2]
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Less fat, more muscle Testosterone is responsible for increased muscle mass
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