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A Bifunctional NAD(+) for Profiling Poly-ADP-Ribosylation-Dependent Interacting Proteins [PMID: 33524253] Laboratory literature summary: A Bifunctional NAD(+) for Profiling Poly-ADP-Ribosylation-Dependent Interacting Proteins

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5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT)a metabolic regulator tied to fat storage, NAD depletion, and reduced energy expenditure