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Proceedings of the National Academy of Sciences of the United States of America, 76 (12), 63196322
These reactions are usually mild and manageable
In most cases, the sulfur burp profile is identical between brand and compounded versions, but individual variation means some people do notice differences
doi: 10.1177/0333102417702132 11
The common ones hit the stomach, mostly in the first few weeks and when the dose goes up
What Clinical Trials Show In large obesity trials: Average weight loss is ~15% of starting body weight with semaglutide 2.4 mg Average weight loss is ~2022% of starting body weight with tirzepatide 15 mg The majority of weight loss occurs within the first year of treatment Plateaus are common after significant weight reduction Some people lose more, some less but a flattening of the weight-loss curve is expected , especially after meaningful progress has already occurred
