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Diabetes 49 , 424430 (2000)
Presented for research literature review only Khaksary Mahabady M et al
all other drugs are at trial endpoint (48-72 weeks)
I didnt realize the hit to my mental health, I didnt realize the hit to my cognition
Consistent with this mechanism, iron deposition in the hippocampal region of patients with type 2 diabetes mellitus (T2DM) is causally linked to cellular damage via oxidative stress, leading to cognitive impairment that is inversely correlated with cognitive performance metrics (Yang et al., 2018)
This framework generates testable predictions and potential monitoring endpointsincluding lean mass trajectory, micronutrient status, fat-soluble vitamin surveillance, and exploratory redox-related biomarkersthat can be evaluated in future longitudinal and interventional studies
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