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After adjusting for insulin resistance, the differences in GLP-1 sensitivity between lean and obese subjects were no longer significant, suggesting that its effects are modulated by the individuals insulin sensitivity status

To support rapid proliferation, cancer cells take up more glucose for glycolysis even in the presence of oxygen, a phenomenon known as the Warburg effect 2

Clinical trial registration EudraCT number 2015-005402-11

A perspective published in the New England Journal of Medicine by Stacie Dusetzina of Vanderbilt University highlighted an important wrinkle in this design

Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion

Injectable GLP-1 and dual agonists command 78.4% of total drug revenue