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Comparison of GLP-1 Receptor Agonists, SGLT-2 Inhibitors, and DPP-4 Inhibitors as an Add-On Drug to Insulin Combined With Oral Hypoglycemic Drugs: Umbrella Review

Overdose symptoms may be similar to the common side effects of GLP-1 drugs, such as nausea and vomiting, but last longer or lead to dehydration in severe cases, the organization added on its website

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Rushing to higher doses increases the likelihood of more pronounced reactions

The remaining 6% difference, just three targeted modifications, accounts for its dramatically extended duration of action