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A subset of senolytic chloroacetamides induces ferroptosis by engaging GPX4 GPX4 is a selenoprotein with glutathione peroxidase activity, which inhibits ferroptosis 38
Brain Dev 17 : 159163
Aaseth J, Alexander J, Alehagen U
Then, BMDMs were exposed to adipocyte CM for 24 h, and harvested for further studies
Secondary endpoints were safety, side effects, and efficacy
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