Enzymatic degradation in the digestive tract substantially reduces bioavailability, often to the point where clinical benefits become questionable
When citing research, we provide context about study design, sample size, and limitations
From 'Laughing Gas' to 'Galaxy Gas': An Updated Review on the Neurological, Pathologic, and Psychiatric Sequelae of Nitrous Oxide Abuse
Future research should focus on larger samples, alternative administration method (such as IV therapy), longer durations, and explore precursor-based therapies like N-acetylcysteine (NAC) that may support intracellular synthesis
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Paulis L, Rajkovicova R, Simko F