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IGF-1 replacement therapy, within physiological ranges, may restore metabolic balance, improving carbohydrate and lipid metabolism while supporting overall metabolic health and nutrient utilization (7)

PCZ could potentially prevent fluid overload, which is associated with a worse prognosis in septic shock [43]

More research is needed to explore the link between the different genetic variants of G6PD and this alternate pathway in Heinz body catabolism that could possibly explain this hematological peculiarity

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The immune system becomes chronically activated, creating systemic inflammation that affects virtually every organ system