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BPC-157 requires robust safety trials in humans first, then trials to determine the dose-response required to elicit meaningful therapeutic regenerative changes, followed by trials to establish the long term safety

Musculoskeletal Repair: Evidence suggests it may aid in repairing damaged ligaments and tendons

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In preclinical research, this mechanism has been associated with selective apoptosis of senescent cells while preserving healthy cellular populations

The investigators evaluated tendon-explant outgrowth, fibroblast proliferation (MTT assay), cell survival under hydrogen peroxide oxidative stress, and fibroblast migration (transwell filter migration assay) in the presence and absence of BPC-157

Consistency matters more than the specific time of day, though some researchers prefer morning injections to manage initial nausea during waking hours when they can eat lightly and stay hydrated