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Acetonitrile and methanol (HPLC/MS grade with 99.9% purity), sodium hydroxide (NaOH), H 2 O 2 (30 wt.% in H 2 O, ACS reagent), ammonium formate ( 99% purity, used for the preparation of the aqueous UPLC-MS/MS eluent), tert-butyl alcohol (TBA, 99.5%), and potassium iodide (KI, 99%) were all purchased from Sigma-Aldrich, New Zealand
This can lead to an increase in blood flow to the brain, which can cause a temporary increase in intracranial pressure and result in a headache
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