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In osteosarcoma radiotherapy, selinexor inhibits CRM1, affecting PHD2 and targeting HIF-1, thereby increasing radiosensitivity 23,55 (Figure 2 and Table 1)

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Journal of Gastroenterology and Hepatology, 2005

To determine whether disruption of claudin-5 cellular localization was dependent on SMAD3, coverslips of bEnd.3 cells were treated with rTGF 1 and SIS3