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However, this has NOT been demonstrated specifically for BPC-157 in any published study

If symptoms persist, consult a healthcare provider

PMID: 3583493

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The BDNF increase from fasting appears to be related to the switch from glucose to ketone metabolism, as ketone bodies like beta-hydroxybutyrate directly stimulate BDNF gene expression in the hippocampus

The designation acknowledges safety data gaps that preclude traditional drug compounding