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So, while there might be a very brief, temporary increase in heart rate post-administration, the long-term downstream effects of the resulting GH pulse can be profoundly beneficial for the cardiovascular system

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Weight loss relieves the pressure on the heart and improves blood vessel function, both of which can help lower blood pressure

Dose adjustments or alternative therapies may be necessary if indigestion or other gastrointestinal symptoms significantly impair quality of life or prevent adequate nutrition

Pediatr Radiol 42 , 699705 (2012)