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Numerous artificial and natural monothiol class I glutaredoxins efficiently reduce HEDS or redox-sensitive fluorescent proteins without a second active-site cysteinyl residue 12,15,18,26,30,31,33,34,35,54,55,56

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The commonly studied oral glutathione dosage ranges from 250 to 500 mg per day

While the KCH criteria had excellent specificity, it was at the expense of sensitivity, yielding a limited ability to distinguish patients who would survive with conservative medical management versus those that would die without a liver transplant