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DOI:10.64898/2026.02.17.706416

In vitro experiments, including MTT and-H2AX assays, demonstrate their selective cytotoxicity towards ATC cells over normal thyroid cells

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This rapid absorption and clearance profile aligns with its physiological role as a mealtime hormone pramlintide is administered immediately before each major meal to replicate the prandial amylin release that is deficient in insulin-treated diabetes

The positive outcomes are currently based on a large body of clinical experience and anonymized case reports rather than large trial data

Do they coincide with dose escalation