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In general mB12/LDFA has a significant influence on redox regulation with medium effect sizes, particularly in the role of positively affecting glutathione metabolism and its precursors, whereas BH4 primarily has a positive effect on markers of oxidative damage as well as methylation metabolism with large effect sizes

Patel et al

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For siRNA transfection, 3.6 l of aliquoted siRNA was dispensed to flat-bottom 96-well plates (Nunc MicroWell, 167008)