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The Weill Cornell retrospective cohort was larger (255 GLP-1RA subjects) but retrospective, meaning causation is harder to establish than in a prospective RCT

Igwebuike UM, Ochiogu IS, Ihedinihu BC, Ikokide JE, Idika IK

Current evidence suggests minimal pharmacokinetic interaction between semaglutide and levothyroxine

Some individuals also report nausea

Semaglutide-based clinical evidence from a post hoc analysis of the SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) trials (SUSTAIN 15