Anti-nitrotyrosine-HGF mAbs (3A11C6 anti-nitroY198-HGF and 6B82C3 anti-nitroY250-HGF) were raised in-house against a synthetic peptides FTSNPEVR nitro Y 198 EV and KFLPER nitro Y 250 PDKGFD, respectively (sites well-conserved in mammals) as described previously 32
20 Possible mechanisms are: natriuresis, due to increased atrial natriuretic peptide secretion, GLP-1R activation in the proximal nephron tubule and Na + /H + transporter inhibition (which reduces sodium reabsorption), as well as vasodilation due to nitric oxide-dependent vasodilation (endothelial GLP-1R activation) and direct effects on smooth muscle cells GLP-1R
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Int J Biotech Bioeng 5:110118 Kim J-H, Kang S-W, Kim S-W, Chang H-I (2005) High-level production of astaxanthin by Xanthophyllomyces dendrorhous mutant JH1 using statistical experimental designs