Normal insulin function is closely related to mitochondrial function and dynamic balance, and insulin resistance directly leads to mitochondrial dysfunction
Particularly, GLP-1RAs have greater hypoglycaemic and weight-loss effects and are attracting attention as a means of intervening in obesity, which is the key basis of type 2 diabetes pathogenesis
G6PD-d may consequently hinder activation, differentiation, proliferation and the expansion of Th1 and CD8 + T cells during acute stimulation 89,118,119
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73 , e13399 (2019)
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