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Surprisingly, we still detected an induction effect of DMF on most of the factors studied despite NRF2 silencing (Fig

Sanitize the rubber stoppers on both vials with alcohol wipes and allow them to air dry

(2) GHK-Cu is a peptide complex made from the tripeptide GHK, composed of glycine, histidine, and lysine, joined to a divalent copper ion (Cu)

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2.3 Cisplatin induces mitochondrial dysfunction When cisplatin enters the mitochondria, it acts directly on the inner mitochondrial membrane, leading to the impairment of the function of the electron transport chain, the reduction of ATP production and the induction of ROS generation (Tan and Song, 2023),these damages further lead to mitochondrial dysfunction, which in turn prompts more ROS production, forming a positive feedback loop (Tan and Vlajkovic, 2023)

Glutathione binds to toxins, heavy metals, and alcohol byproducts, making them water-soluble so they can be flushed out through the bodys natural detoxification processes