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Weight loss is the most visible change, with clinical trials demonstrating average reductions that vary by medication: approximately 5-10% with liraglutide (Saxenda), 15-17% with semaglutide 2.4mg (Wegovy) in the STEP trials, and up to 20% with higher doses of tirzepatide in the SURMOUNT programme
Body weight includes: body fat muscle tissue water retention glycogen storage The goal for most individuals is to reduce excess fat while maintaining lean muscle
Dose the single dose being measured, in milligrams
Semaglutide mimics your natural GLP-1 hormone, signaling your brain that you are full
When to seek medical advice: You should contact your GP or diabetes specialist nurse if nightmares are persistent, distressing, or accompanied by other concerning symptoms such as severe mood changes, anxiety, or depression
You Dont Need Maximum Results: If losing 30-35 pounds satisfies your goals, semaglutide may be sufficient without needing tirzepatides extra potency
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