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SLC25A39 as well as mitochondrial GSH may also represent promising drug targets for cancer, since manipulating SLC25A39 functioning or mitochondrial GSH in tumor cells may induce selective oxidative stress, leading to cell death

Intracellular metabolite concentrations have to fine-tune the signaling networks governing metabolic pathways independently of the environment to ensure a balance between the availability of nutrients and the cellular capacity to use them effectively

Tirzepatide (15 mg weekly) drives 15.7% weight loss over 72 weeks in patients with obesity and T2D (45) and 22.5% weight loss in patients with obesity alone (46)

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L-carnitine may have therapeutic role in liver diseases including non-alcoholic steatohepatitis, cirrhosis, hepatocellular carcinoma, alcoholic fatty liver disease, and viral hepatitis