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Rates of obesity worldwide have more than doubled since 1990 among adults and have increased more than fourfold among children and adolescents.[1] Obesity is associated with a number of health conditions, including:[2] High blood pressure High cholesterol Heart disease Type 2 diabetes Asthma Sleep apnea Osteoarthritis and other musculoskeletal disorders Gallstones and gallbladder disease Anxiety and depression Low self-esteem Decreased quality of life Increased risk of being bullied, especially in children and adolescents Certain types of cancer With so many potential health impacts, many people are exploring medical options to support weight loss
Constipation from semaglutide is typically mild to moderate, but it can still impact your daily well-being
If levels of oxalate in the glomerular filtrate increase (hyperoxaluria) it can chelate Ca 2+ ions forming the insoluble compound, calcium oxalate
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This work adds a new layer to our understanding of how these drugs function, and may help guide future therapeutic strategies beyond weight loss alone