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Adapted from Jastreboff et al

The hepatic microenvironment reprograms the metabolism and function of immune cells, while aberrant immune responses intensify hepatic metabolic stress

A 753-P: Tirzepatide improves HRQoL compared with insulin lispro in poorly controlled basal insulin-treated adults with long-standing T2D (SURPASS-6)

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Mounjaro is a licensed medicine, while Reta products are research-use-only products and are not supplied for personal use

Afamelanotide is FDA-approved as Scenesse for erythropoietic protoporphyria via a subcutaneous implant