The economic problem is that settlements involving large payments from innovator to generic leave the payer the patient or insurance company paying branded prices for an unnecessarily long period, with the settlement value effectively extracted from that payer through artificially maintained branded pricing
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PMID: 35 ZhengZZongYMaYTianYPangYZhangCet al
However, if metformin is still not tolerated, the presence (or absence) of comorbidities helps inform the choice of alternative medications
doi:10.1093/bioinformatics/btz931 Kanehisa M, Goto S
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