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Slide from FLOW session, 61st European Renal Association Congress Sample Size and Analytic Plan This trial was event-driven, with a minimum of 854 primary outcome events (including 515 kidney events) which would provide 90% power to detect a 20% risk reduction

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doi:10.3389/fmed.2025.1683970

Research from the National Institute of Diabetes and Digestive and Kidney Diseases tracking long-term weight maintenance shows that individuals who lost significant muscle during weight loss had 3.8 times higher regain rates than those who preserved lean mass

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