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3, the inhibitors targeting NADPH-synthesis enzymes are being extensively developed

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The proposed protective mechanisms are thought to parallel those implicated in GI infection prophylaxis, primarily by modulating immune function at both local and systemic levels (488)

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In this compound, penicillamine replaces the cysteine moiety of CAO

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Pericyte-targeting drug delivery and tissue engineering

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10 Finally, major surgery (eg, removal or replacement of all or part of the bladder, and/or rerouting of the urinary stream) can be effective but has a high complication rate and is a last option for those with severe, debilitating, intractable symptoms

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