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While the UPR initially enhances proteasome activity to manage misfolded proteins, chronic ER stress can overwhelm the UPS, compromise proteasome function and exacerbate cellular dysfunction

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[Accessed on 24th June 2022] 3

As a result, Liraglutide is growing in popularity in treating chronic weight management

A research study showed that a GLP-1 agonist, when combined with healthy lifestyle changes like diet and exercise, predictably helped reduce weight by about 15%, compared to 2.5% in patients who didnt take the medication