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GLP-1, or glucagon-like peptide-1, is a naturally occurring hormone that plays a critical role in regulating appetite, blood sugar, and metabolism
Previous studies in Zucker rats suggest that GIP signalling is muted during obesity [14]
In contrast, Wegovy targets only the GLP-1 receptor, which still provides substantial weight loss benefits but generally at a lower magnitude
What It Does Decreased appetite and cravings, weight loss, A1C reduction, and improved cardiometabolic measures
In 2023 and 2024 , respectively, Ozempic and Wegovy were also approved to reduce the risk of major cardiovascular problems (e.g
The exact link between GLP-1 drugs and gastroparesis isnt clear, and some experts have expressed doubt that the medications cause permanent effects
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