Importantly, both drugs produced clinically meaningful outcomes
Then come the labs elevated fasting glucose or an A1C creeping toward pre-diabetes or early type 2 diabetes
Taking oral steroids with food (even small amounts), splitting doses throughout the day, and using liver support supplements can help minimize combined GI effects
Feeding the good guys, such as anti-inflammatory butyrate-producers and Bifidobacteria, and encouraging the right balance of flora is an important part of reducing methane production and long term rebalancing of the microbiome
More often, shedding is related to weight loss triggers like calorie deficit, stress, and nutrient gaps
Avoid using the medication if you have a history of medullary thyroid carcinoma, pancreatitis, severe gastrointestinal disorders, or multiple endocrine neoplasia type 2 (MEN2) syndrome