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29(2 Suppl): S126S131.CrossRefGoogle ScholarPubMed Lindenbaum, J, Healton, E, Savage, D
The enteric nervous system is part of the autonomic nervous system, which also includes the sympathetic (flight, fright or freeze) and the parasympathetic (rest and digest) nervous systems
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Results from a phase 1 trial have supported further clinical evaluation with a dose-dependent WL up to 14.5% with AMG133 compared to 1.5% with placebo by day 85 [59]
Both remain preclinical compounds, and findings have not been confirmed in human trials