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Moreover, instead of promoting immunity against tumours, STING activation in B cells induced the secretion of anti-inflammatory cytokine IL-35 that impeded the actions of NK cells and led to poorer outcomes in mouse models 22
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Sustained elevated GH and IGF-1 are the pharmacologic feature
Some Sjogren's patients report that tirzepatide worsens dry mouth , a symptom they already struggle with
Moreover, more potential molecules and traditional medicines/extracts with antioxidant activity are needed to be identified, which would lay the foundation for developing PIPN-tailored drugs
However, these side effects are temporary and will subside quickly
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