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Most clinical trials studied 68 weeks of treatment, but many people continue indefinitely
Acarbose, a representative -GI, has been shown to increase the abundance of culturable Bifidobacterium longum and Enterococcus faecalis, reduce the abundance of Enterobacteriaceae, and lower LPS levels in patients with T2DM following treatment (76)
9 While it is unclear if this risk applies to humans, caution is advised
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Across multiple national and multinational healthcare databases, GLP-1 use was associated with lower rates of colorectal cancer compared with non-use and with other antidiabetic therapies, including insulin and sulfonylureas
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