Many offer significant protective benefits for the heart and kidneys, reducing the risk of major cardiovascular events like heart attack and stroke
access is limited to approved clinical trials, and no EAMS designation has been granted, so adverse events must be reported through trial pharmacovigilance processes rather than Yellow Card
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(Adding that even if youre not pregnant, it's essential that reliable contraception should be used while on these medications.) From a gynecological perspective, while active pregnancy is a clear contraindication, most gynecological conditions don't automatically disqualify someone from GLP-1 use. However, she stresses that patients with severe endometriosis or other conditions affecting the digestive system should have detailed discussions with their healthcare providers
"And the subjects in the trial were still losing weight at the end." The best comparable results come from last year's clinical trial results for the diabetes drug Mounjaro (tirzepatide), which after 72 weeks had produced an average weight loss of more than 22%, Kaplan said