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Likewise, ChREBP knockout protected against fructose-induced steatosis in mice, but substantially increased histological liver damage as a result of enhanced cholesterol synthesis and subsequent cytotoxicity [50]
Hum Genet Genomics Adv 4:100150
It impacts school, work, and social interactions
MRI-guided platforms support noninvasive assessment of tumor distribution, vascular permeability and response, while PET- and SPECT-based approaches provide quantitative whole-body biodistribution data for tumor accumulation, off-target exposure and patient-level variability [72, 74, 86,87,88]
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