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Evidence snapshot: The strongest human evidence comes from a 2-year randomized controlled trial in 65 healthy older adults (Nass et al., 2008, Annals of Internal Medicine) showing sustained GH/IGF-1 increases and preserved fat-free mass, plus an earlier short-term human polysomnography study on sleep (Copinschi et al., 1997, Neuroendocrinology, PMID 9349662)

Research demonstrates that it promotes synapse formation at approximately 10 million times the potency of BDNF itself, working through the hepatocyte growth factor (HGF) and c-Met receptor pathway

Researchers value its sterile composition, multi-use design, and easy handling for controlled investigational procedures

and effect on daily activities

Vitamin B12 plays a key role in converting food into energy

By month 6, the gains had further accumulated